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maximum 50k data
Found 58 of ic50 data for polymerid = 50004074
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266136((R)-3-(4-iodobenzylthio)-2-((S)-3-mercapto-2-methy...)
Affinity DataIC50:  15nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266173((R)-3-(4-tert-butylbenzylthio)-2-((S)-3-mercapto-2...)
Affinity DataIC50:  24nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272201((2S,5S)-5-(4-tert-butylbenzylthio)-1-((S)-3-mercap...)
Affinity DataIC50:  31nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272202((2S,5S)-5-(4-cyclohexylbenzylthio)-1-((S)-3-mercap...)
Affinity DataIC50:  34nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266244((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-(m...)
Affinity DataIC50:  46nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272142((2S,5S)-5-(4-isopropylbenzylthio)-1-((S)-3-mercapt...)
Affinity DataIC50:  52nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266316((R)-3-(2-(4-cyclohexylphenyl)propan-2-ylthio)-2-((...)
Affinity DataIC50:  55nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266247((2R)-3-(1-(4-isopropylphenyl)ethylthio)-2-((S)-3-m...)
Affinity DataIC50:  55nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266248((2R)-3-(1-(4-isopropylphenyl)propylthio)-2-((S)-3-...)
Affinity DataIC50:  67nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266171((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-pr...)
Affinity DataIC50:  72nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266280((R)-3-(2-(4-isopropylphenyl)propan-2-ylthio)-2-((S...)
Affinity DataIC50:  79nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266175((R)-3-(4-cyclohexylbenzylthio)-2-((S)-3-mercapto-2...)
Affinity DataIC50:  79nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266279((2R)-3-((4-isopropylphenyl)(phenyl)methylthio)-2-(...)
Affinity DataIC50:  91nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272200((2S,5S)-5-(4-(methylthio)benzylthio)-1-((S)-3-merc...)
Affinity DataIC50:  120nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266138((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-(t...)
Affinity DataIC50:  140nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266245((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-(m...)
Affinity DataIC50:  158nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266276((2R)-3-(1-(4-isopropylphenyl)butylthio)-2-((S)-3-m...)
Affinity DataIC50:  180nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266172((R)-3-(4-isopropylbenzylthio)-2-((S)-3-mercapto-2-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266315((2R)-3-((4-cyclohexylphenyl)(phenyl)methylthio)-2-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266170((R)-3-(4-ethylbenzylthio)-2-((S)-3-mercapto-2-meth...)
Affinity DataIC50:  280nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272203((2S,5R)-5-(4-isopropylbenzylthio)-1-((S)-3-mercapt...)
Affinity DataIC50:  290nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266209((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-(t...)
Affinity DataIC50:  400nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266079((R)-3-(4-(dimethylamino)benzylthio)-2-(2-mercaptoa...)
Affinity DataIC50:  470nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266278((2R)-3-(1-(4-isopropylphenyl)pentylthio)-2-((S)-3-...)
Affinity DataIC50:  510nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266277((2R)-3-(1-(4-isopropylphenyl)-2-methylpropylthio)-...)
Affinity DataIC50:  520nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266213((R)-3-(4-cyanobenzylthio)-2-((S)-3-mercapto-2-meth...)
Affinity DataIC50:  525nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266174((R)-3-(biphenyl-4-ylmethylthio)-2-((S)-3-mercapto-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266135((R)-3-(4-bromobenzylthio)-2-((S)-3-mercapto-2-meth...)
Affinity DataIC50:  610nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266210((R)-3-(4-ethoxybenzylthio)-2-((S)-3-mercapto-2-met...)
Affinity DataIC50:  640nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272143((2S,5S)-5-(4-isopropylphenethylthio)-1-((S)-3-merc...)
Affinity DataIC50:  790nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272199((2S,5S)-1-((S)-3-Mercapto-2-methyl-propionyl)-5-(2...)
Affinity DataIC50:  840nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266212((R)-3-(4-(diethylamino)benzylthio)-2-((S)-3-mercap...)
Affinity DataIC50:  891nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272141((2S,5S)-1-((S)-3-mercapto-2-methylpropanoyl)-5-(na...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272062((2S,5S)-1-((S)-3-mercapto-2-methylpropanoyl)-5-(3-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266108((R)-3-(4-(dimethylamino)benzylthio)-2-((R)-3-merca...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266133((R)-3-(4-fluorobenzylthio)-2-((S)-3-mercapto-2-met...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266211((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-ph...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266134((R)-3-(4-chlorobenzylthio)-2-((S)-3-mercapto-2-met...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266208((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-me...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272144((2S,5S)-5-(3-(4-isopropylphenyl)propylthio)-1-((S)...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272060((2S,5S)-5-(benzylthio)-1-((S)-3-mercapto-2-methylp...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266243((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-ni...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272061((2S,5S)-1-((S)-3-mercapto-2-methylpropanoyl)-5-(ph...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266137((R)-2-((S)-3-mercapto-2-methylpropanamido)-3-(4-me...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266109((2R)-3-(4-(dimethylamino)benzylthio)-2-(3-mercapto...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50272099((2S,5S)-1-((S)-3-mercapto-2-methylpropanoyl)-5-(na...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of guinea pig lung leukotriene A4 hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266246((R)-3-(4-isopropylbenzylthio)-2-((S)-3-mercapto-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266110((R)-3-(4-(dimethylamino)benzylthio)-2-(4-mercaptob...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266107((R)-3-(4-(dimethylamino)benzylthio)-2-(3-mercaptop...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Cavia porcellus)
Santen Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50266106((R)-3-(4-(dimethylamino)benzylthio)-2-((R)-2-merca...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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